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Nel grande weekend di motori che vede la Formula 1 tornare in pista a Imola, su Sky e in streaming su NOW la MotoGP fa il suo ingresso. Scopri di più

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L’albero di giada, considerato un vero portafortuna, è una pianta succulenta molto resistente che richiede poche cure: scopriamo come coltivarla.

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The Granny Stripe Shawl is worked flat from the top down using the timeless three double crochet clusters. The number of clusters increases in each row, creating a beautiful drape that flatters the shoulders. Crochet the classic Granny stripe rows until you reach your desired length. The shawl is finished with a pretty traditional scalloped edge, framing the upper part and sides first, then the bottom edge is made. It’s a perfect scrappy project to use up all your yarn scraps and enjoy both the process and the finished piece.

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The heat is on in this fast paced action-comedy starring Eddie Murphy as Axel Foley, a street smart Detroit cop tracking down his best friend's killer in Beverly Hills.

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Provided to YouTube by RCA Records Label Nashville Thank God · Kane Brown · Katelyn Brown Different Man ℗ 2022 Sony Music Entertainment. All rights reserved. Released on: 2022-09-09 Associated Performer: Kane Brown & Katelyn Brown Composer, Lyricist: Christian Stalnecker Composer, Lyricist: Kyle Fishman Background Vocal: Shy Carter Steel Guitar: Paul Franklin Programmer, Synthesizer, Editor: David Huff Composer, Lyricist: Jaxson Free Keyboards: Charlie Judge Composer, Lyricist: Josh Hoge Bass: Jimmie Lee Sloas Drums, Percussion: Aaron Sterling Composer, Lyricist: Jared Mullins Acoustic Guitar: Ilya Toshinskiy Electric Guitar: Derek Wells Overdub Engineer, Producer: Dann Huff Recording Engineer: Buckley Miller Assistant Engineer: Zach Kuhlman Mixing Engineer: Drew Bollman Editor: Chris Small Mixing Engineer: Justin Niebank Mastering Engineer: Adam Ayan Project Coordinator: Mike "Frog" Griffith Auto-generated by YouTube.

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In the video captured by Átlátszó, the perpetrators committed the fraud in broad daylight near a voting station on a main road. Several voters were involved in

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Provided to YouTube by The Orchard Enterprises Harvey · Her's Invitation to Her's ℗ 2018 Heist or Hit Released on: 2018-08-24 Producer: Saam Jafarzadeh Auto-generated by YouTube.

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A standard-size painting can be completed by a Chinese master copyist in two to three hours.

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(Bloomberg) -- Zhang Haitao was a basketball-loving teenager who dreamed of going to a specialized sports high school when he got a pain in his right arm that just wouldn’t go away. It turned out to be acute lymphoblastic leukemia.The discovery set Zhang and his family, from a village deep in the mountains of southwestern China's Sichuan province, on a journey familiar to most cancer patients — a revolving door of hospital visits, blood tests and three rounds of chemotherapy. It was then that Zhang’s doctor suggested a last-ditch option: an experimental gene therapy being trialed by a Chinese startup called Gracell Biotechnology Ltd.After spending three weeks in the hospital in May — during which white blood cells were removed from his body, genetically engineered, and then infused back in — an analysis of Zhang’s bone marrow in June showed his body was clear of cancer.Seven months later, monthly medical tests conducted at a hospital in the nearby Chinese metropolis of Chongqing show he remains cancer free. “I don’t remember much about the treatment as I had a fever throughout,” said Zhang, who’s now almost 16 and spends his days playing video games and texting his friends. “It seems like a new solution that will give people hope.”Read more about how China is overhauling its healthcare systemThe therapy Zhang received was Chimeric Antigen Receptor-T cells, known as CAR-T, and it’s being hailed as one of the most exciting developments in the quest to cure cancer. First developed by Israeli scientist Zelig Eshhar in the 1980s, CAR-T re-works the genes of the body’s own immune cells so that they actively seek out and destroy cancer cells. While it’s been embraced by researchers and drugmakers around the world, perhaps nowhere is CAR-T having more impact — and being pushed dangerously close to its limits — than in China, home to the world’s biggest cancer population and some of the most ambitious experiments.CAR-T works by supercharging T-cells, the body’s main line of defense against disease, so that they latch onto and destroy cancer. In clinical trials, leukemia patients who failed to respond to other therapies have shown remission rates of over 90% within two months of treatment.Though drug giants Novartis AG and Gilead Sciences Inc. have been marketing CAR-T globally since 2017, it’s expensive. The process of engineering an individual’s cells in a laboratory and then replicating them has also meant that some patients with more aggressive cancers can die waiting for treatment.That’s where Gracell’s therapy was revolutionary. Instead of the two to three weeks taken by current treatments from American and European drug makers, the Shanghai-based company — set up by a group of veteran Chinese cell-therapy researchers — is churning out cancer-killing immune cells overnight.And they’re doing it much cheaper in some cases than global pharmaceutical giants. Gracell has developed a process using genetic engineering that speeds up the cell production stage, according to founder William Cao Wei. Gracell plans to price its CAR-T treatment for about 500,000 yuan ($71,000), well below the $475,000 price tag for Novartis’ Kymriah, the Swiss company’s CAR-T therapy used to treat the type of blood cancer that Zhang had. A similar treatment from Gilead, based in Foster City, California, costs $373,000.The aging population and a raft of lifestyle factors mean that more new cancer patients are emerging in China than anyplace else in the world, giving the country a significant stake in the global fight to find a cure. Emboldened by the government’s push to become a scientific superpower and to dominate the field of genetics, Gracell and other Chinese biotech startups are racing ahead, with China likely to approve CAR-T for widespread use as early as next year. Up for grabs is a market for cancer drugs and experimental treatments that has exploded to $133 billion a year worldwide, according to life sciences researcher Iqvia Institute.“There can be both cooperation and competition between us and CAR-T developers in developed markets,” said Cao, who is also Gracell’s chief executive officer. “But there will definitely be competition.” That drive to forge ahead — and in front — can be seen in the way China is approaching regulation of CAR-T. The country is weighing new rules that would loosen oversight of the revolutionary technology, allowing academic ethics committees within hospitals to approve new CAR-T treatments and then administer them to patients for a fee.That would markedly loosen China’s current framework, which is presently in line with the approach taken by regulatory bodies like the U.S Food and Drug Administration and the European Medicines Agency. These entities are the sole authorities in their jurisdictions that evaluate and approve all CAR-T therapies before they are cleared for public use.There is concern among researchers, regulatory experts and drugmakers themselves that allowing hospitals to market treatments for a fee could cause profit-making to trump ethical considerations. In a 2016 case widely reported in the Chinese media, a 22-year-old college student with a rare type of tissue cancer called synovial sarcoma died after going through an experimental cell therapy at a Beijing hospital.“Hospitals can become both players and referees at the same time”Before his death, the patient posted an essay online claiming the hospital had falsely advertised the treatment’s effectiveness, and that Chinese search engine Baidu Inc. had displayed the hospital’s advertising so that it appeared like a credible search result rather than a paid commercial. The essay went viral and sparked an outcry on Chinese social media over the ethics of private hospitals and the regulation of therapies for serious illnesses.Censured by the Cyberspace Administration of China, Baidu responded by restricting the number of sponsored posts to 30% of a results page, and established a 1 billion yuan fund to fight fraud. The hospital did not respond to requests for comment.It’s not the only death allegedly linked to genetic cell therapy in China. Last year, a hospital in the eastern city of Xuzhou was sued over the death of a lymphoma patient who died after receiving a CAR-T treatment. The patient developed severe side effects, including bleeding within the abdomen. The patient’s family argued that the treatment led to his death, but the hospital and doctor said it was the result of late-stage cancer. A court is yet to rule on the case.China’s proposed new framework is reminiscent of its wider approach to the regulation of science, an area President Xi Jinping has prioritized as part of his ambition to cement the country as a world power.The research of He Jiankui, an American-educated Chinese scientist whose revelation last year that he’d edited the genes of twin baby girls ignited a global firestorm, was signed off by the ethics committee of a Shenzhen hospital. The experiment, which He claimed made the twins immune to HIV, wasn’t backed by peer-reviewed data and still hasn’t been verified. Scientists around the world have condemned it as an irresponsible use of a technology that has the capacity to alter the very building blocks of life. The long-term effects of Crispr, the gene-snipping tool used by He and embraced by Chinese researchers, are also yet to be fully understood.China’s new draft rules on CAR-T could give rise to the same scenario, critics say.There’s no guarantee that the hospital committees have the qualifications to evaluate such a complicated therapy, said Tao Xin, a Washington, D.C.-based lawyer at Hogan Lovells LLP who specializes in the health-care regulatory law of both the U.S. and China.“The proposal indicates that hospitals can charge a fee for the therapy, in addition to approving its own therapy,” he said. “With these two combined, are we going to see a replay of the 2016 incident? If there’s money to be made and I get to decide whether to do it or not, that’s really controversial.”Read about how Crispr is being used in China’s quest to make a super pigGracell’s Cao is also critical of the new framework as it removes the role of an independent entity that evaluates the therapy’s safety and efficacy: “Hospitals can become both players and referees at the same time.”Novartis and Gilead declined to comment on China’s regulatory plans, while a spokesman for the National Health Commission, the body in charge of governing the country’s health sector, said that the proposed new rules are still under discussion.Read about how Chinese parents are using DNA tests to map out their children’s livesMeanwhile, Chinese companies are racing ahead on CAR-T and attracting hundreds of millions of dollars from investors like Singapore’s sovereign wealth fund Temasek Holdings Pte Ltd, as well as global pharmaceutical giants. Venture capital investment in Chinese biotech firms climbed to $17.6 billion last year, quadruple the amount from 2015, according to consultancy ChinaBio LLC. Gracell — which counts Temasek and Lilly Asia Ventures, the venture capital firm spun off from Eli Lilly & Co. as investors — says 32 of the 35 patients it’s enrolled in its China-based trials over the past year have gone into complete remission “with minimal residual disease tested negative” four weeks after the CAR-T infusion — a clinical term that basically means there was no evidence of disease remaining in their bodies, the highest possible efficacy level for a therapy.Other Chinese startups like Nanjing Legend, a unit of Hong Kong-listed Genscript Biotech Corp., and U.S.-listed Cellular Biomedicine Group Inc., have developed similar capabilities.In 2018, Novartis paid $40 million for a 9% stake in Shanghai-based Cellular Biomedicine, and will use their cell therapy facility to manufacture its Kymriah treatment, which is currently being assessed for approval by China’s drug regulator. The startup is also developing its own CAR-T therapies and testing their potential against solid tumors, not just blood cancers. Chief Executive Officer Tony Liu Bizuo said Cellular Biomedicine’s digitized and automated process cuts the cell engineering time from four weeks to less than 10 days.Cellular Biomedicine is now mulling building a bigger cell production facility with the Shanghai government, as demand for cell therapy grows and on expectations more commercial CAR-T treatments will be approved in China in the coming years. In a sign of the support startups are getting from the authorities, the city’s government has earmarked a 4 million square feet space for cell therapy research. Of the 21 cell therapies currently in clinical trials approved by China’s drug regulator, 11 are being conducted in the lab, which is fast becoming the nation’s CAR-T Ground Zero.The next frontier is to make CAR-T as accessible as any other drug, and Chinese startups are at the leading edge. Dubbed “universal CAR-T,” this involves finding a way to take T-cells from healthy people and engineering them so that they can be infused into any cancer patient. Gracell is studying the use of donor white blood cells, marking a step toward that goal. Other startups like French company Cellectis SA are also racing to make universal CAR-T a reality.“I’m very impressed with the pace of technological progress in China and the expansion of CAR-T research coming so rapidly,” said Bruce Levine, a professor specializing in cancer gene therapy at the Perelman School of Medicine at the University of Pennsylvania.“We all want these therapies to move fast and some are very good, but we need to be aware that some could be moving too fast for their expertise, even if they have very good intentions,“ he said.Read about how a Chinese genetics giant wants to tailor drugs to people’s DNAAfter a year in and out of hospital, Zhang, the teenage cancer patient in Chongqing, is starting to make plans for the future. If it wasn’t for the leukemia, he’d be in his first year of high school now.“I don’t think I can go to sports school anymore, but I hope to learn a professional skill,” said Zhang, who’s now a foot taller than his aunt, Chen Chunhua, his primary caregiver. “I want to grasp this chance I have.”While China’s approach to CAR-T may be criticized as moving too fast, Chen, who left her job at a ceramics factory to care for Zhang when he got sick, is thankful he had access to the treatment, which wouldn’t have been possible in China had the boy fallen ill just a year earlier.“I’m so happy we had this option within China,” she said. “It really helps to lessen our burden.”  \--With assistance from Dong Lyu.To contact the editor responsible for this story: Rachel Chang at wchang98@bloomberg.net, Anjali CordeiroFor more articles like this, please visit us at bloomberg.com©2019 Bloomberg L.P.

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I do Not own the Copyright for the Audio. Just Enjoy. UK Pressing.

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Thank you for your support ❤️ Please Like Comment and Subscribe #michaeljordan #jamesjordan #nba #davidstern #chicagobulls #bostonceltics #larrybird #scottiepippen #magicjohnson #isaiahthomas #djvladtv #jamesslimbouler #nbcsports #northcarolinatarheels #danielgreen #larrydemery #espn #foxsports #truecrimestories ##truecrime #truecrimestories #unsung #biography #philjackson #kobebryant

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A partire da oggi, su ELEVEN SPORTS sarà possibile acquistare una gift card da € 39, 99, come idea regalo per Natale 2022. Scopri di più

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In Flight is a live album by Alvin Lee & Co. It was released in 1974. Album Track List: Side 1 1. "Got to Keep Moving" - 5:02 2. "Going Through the Door" - 4:21 3. "Don't Be Cruel" (Elvis Presley, Otis Blackwell) - 2:39 4. "Money Honey" (Jesse Stone) - 3:05 5 "I'm Writing You a Letter" - 4:52 Side 2 1. "You Need Love Love Love" - 5:24 2. "Freedom for the Stallion" (Allen Toussaint) - 6:26 3. "Every Blues You've Ever Heard" - 5:24 4. "All Life's Trials" - 2:59 Side 3 1. "Intro" (Alvin Lee & Company) - :53 2. "Let's Get Back" - 4:58 3. "Ride My Train" - 4:14 4. "There's a Feeling" - 4:02 5. "Running Round" - 5:38 Side 4 1. "Mystery Train" (Herman Parker Jr., Sam Phillips) - 4:42 2. "Slow Down" (Larry Williams) - 3:38 3. "Keep a Knockin'" (Richard Penniman) - 2:14 4. "How Many Times" - 2:04 5. "I've Got Eyes for You Baby" - 3:36 6. "I'm Writing You a Letter" - 4:18 Bonus Tracks not on original LP "Somebody Callin' Me" - 6:26 "Put It in a Box" - 8:06 Alvin Lee: Alvin Lee - vocals & guitar Mel Collins - sax & flute Ian Wallace - drums Tim Hinkley - keyboards Allan Spenner - bass Neil Hubbard - guitar Dylan Birch,Frank Collins & Paddie McHugh - backing vocals CD 1998 ,Bonus Tracks, Live, Remastered, Repertoire Records ★ DISCLAIMER ★ I do not own the anime, music, artwork or the lyrics. All rights reserved to their respective owners!!! This video is not meant to infringe any of the copyrights. This is for promote. ★ Copyright Disclaimer ★ Title 17, US Code (Sections 107-118 of the copyright law, Act 1976): All media in this video is used for purpose of review & commentary under terms of fair use. All footage, & images used belong to their respective companies. Fair use is a use permitted by copyright statute that might otherwise be infringing.

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We live in a world, according to N. Katherine Hayles, where new languages are constantly emerging, proliferating, and fading into obsolescence. These are languages of our own making: the programming languages written in code for the intelligent machines we call computers. Hayles’s latest exploration provides an exciting new way of understanding the relations between code and language and considers how their interactions have affected creative, technological, and artistic practices. My Mother Was a Computer explores how the impact of code on everyday life has become comparable to that of speech and writing: language and code have grown more entangled, the lines that once separated humans from machines, analog from digital, and old technologies from new ones have become blurred. My Mother Was a Computer gives us the tools necessary to make sense of these complex relationships. Hayles argues that we live in an age of intermediation that challenges our ideas about language, subjectivity, literary objects, and textuality. This process of intermediation takes place where digital media interact with cultural practices associated with older media, and here Hayles sharply portrays such interactions: how code differs from speech; how electronic text differs from print; the effects of digital media on the idea of the self; the effects of digitality on printed books; our conceptions of computers as living beings; the possibility that human consciousness itself might be computational; and the subjective cosmology wherein humans see the universe through the lens of their own digital age. We are the children of computers in more than one sense, and no critic has done more than N. Katherine Hayles to explain how these technologies define us and our culture. Heady and provocative, My Mother Was a Computer will be judged as her best work yet.

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Pre-order your copy of The Road to You! The Road to You is launching this March and I can’t wait to share this special story with all of you!   Becoming a parent is a journey unlike any other, one filled with longing, patience, and...

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Set 1 Feel Like A Stranger, West L.A. Fadeaway, Easy To Love You, Beat It On Down The Line, It Must Have Been The Roses, The Last Time, Picasso Moon, Don't...

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Fotografías recopiladas por Maxar revelan la enorme destrucción en edificios y estructuras en el norte de la franja tras tres semanas de ofensiva israelí

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Monti, colline, mare, fiumi, ma anche laghi affascinanti. L’Emilia Romagna nasconde piccoli paradisi perfetti per essere visitati a settembre.

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Track 6 from their seventh album “Permanent Waves” released in 1980 copyright Anthem Records. Their previous two albums had been recorded at a farm in the countryside of Wales and the band appreciated the solitude they experienced during those recording sessions. Wanting a change of scenery for this album, the band chose Le Studio in Morin Heights, in the Laurentian Mountains of Quebec and closer to home. While maintaining their sound, this album featured songs that were shorter and more radio-friendly and designed to appeal to a wider audience. Most became hits and there were also a couple of lengthy deep cuts for their many faithful fans. The album received excellent reviews and reached No. 3 in Canada & the U.K. and No. 4 on the Billboard chart. It was certified Gold in the U.K. and Platinum in Canada and the U.S. This was their fifth album cover designed by Hugh Syme, who would be involved with all their subsequent releases. Written by Neil Peart, Geddy Lee & Alex Lifeson and produced by Rush & Terry Brown. RIP Neil Peart. Featuring: Geddy Lee – Lead vocals, bass, Minimoog, Oberheim polyphonic, Oberheim OB-1 & Moog Taurus bass pedals synthesizers Alex Lifeson– Lead, rhythm, acoustic, 12-string electric, 12-string acoustic & Moog Taurus bass pedals synthesizer Neil Peart – Drums, tympani, timbales, orchestra bells, tubular bells, wind chimes, bell tree, triangle & crotales I. Tide Pools When the ebbing tide retreats along the rocky shoreline It leaves a trail of tidal pools in a short-lived galaxy Each microcosmic planet a complete society A simple kind mirror to reflect upon our own All the busy little creatures chasing out their destinies Living in their pools they soon forget about the sea Wheels within wheels in a spiral array A pattern so grand and complex Time after time we lose sight of the way Our causes can't see their effects II. Hyperspace A quantum leap forward in time and in space The universe learned to expand The mess and the magic, triumphant and tragic A mechanized world out of hand Computerized clinic for superior cynics Who dance to a synthetic band In their own image their world is fashioned No wonder they don't understand Wheels within wheels in a spiral array A pattern so grand and complex Time after time we lose sight of the way Our causes can't see their effects III. Permanent Waves Science, like nature, must also be tamed With a view towards its preservation Given the same state of integrity It will surely serve us well Art as expression, not as market campaigns Will still capture our imaginations Given the same state of integrity It will surely help us along The most endangered species: the honest man Will still survive annihilation Forming a world, a state of integrity Sensitive, open and strong Wave after wave will flow with the tide And bury the world as it does Tide after tide will flow and recede Leaving life to go on as it was

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Provided to YouTube by Universal Music Group State Of Emergency · Papa Roach Metamorphosis ℗ 2009 DGC/Interscope Records Released on: 2009-01-01 Composer Lyricist: T. Esperance Composer Lyricist: j. shaddix Composer Lyricist: J. Michael Auto-generated by YouTube.

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Ti va un dolce Botega Caffe Cacao? Scopri il nostro store più vicino, siamo in tutta l'Italia.

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A nineteen-year-old buys cattle. The brand on their hips: four sixes in a row. He does not know where it came from. Neither does anyone else. The poker story is a lie. Drought. A deal across the Red River. A son who fails West Point and finds something else entirely. A president on a wolf hunt. A blizzard that kills two thousand head in a single night. Oil beneath the grass. A will that skips a generation. Cowboys who pose for cigarette ads and do not live to see the money run out. 155 years. Five owners. Three divisions. One brand that nobody can explain. The Four Sixes still runs cattle on horseback. The cowboys still saddle up before dawn. But the legend and the truth are not the same thing. They never were. #6666ranch #documentary #realestate #texasranch #history Copyright & Fair Use Notice * This video is a non-commercial, educational history documentary produced for research and for purposes of commentary, critique, and analysis. * Certain archival photographs and video clips appear here under the Fair Use doctrine (Section 107 of the U.S. Copyright Act), including use for commentary and criticism, news reporting, instruction, scholarship, and research.

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Provided to YouTube by Space Shower FUGA 僕の胸でおやすみ · Takahiko Ishikawa PLAY FOLK SONGS ℗ 2010 birdie house Released on: 2010-02-24 Music Publisher: Copyright Control Composer: Yamada Tsuguto Auto-generated by YouTube.

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Provided to YouTube by Evolve P&D Crooktown · Eddie Kaine · Big Ghost Ltd. · Rim Last Exit To Crooklyn ℗ 2024 Big Ghost Ltd. Music Released on: 2024-04-02 Producer: Big Ghost Ltd. Music Publisher: Copyright Control Author: Eddie Kaine Auto-generated by YouTube.

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Stockton leaders are moving forward with plans to install license plate readers on city streets to aid police in reducing crime. Here's how they work.

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Naomi Loses Her Husband and Sons In the days when the judges ruled,#:1 Traditionally judged there was a famine in the land. So a man from Bethlehem in Judah, together with his wife and two sons, went

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Provided to YouTube by Universal Music Group Electric City · The Black Eyed Peas THE E.N.D. (THE ENERGY NEVER DIES) ℗ 2009 Interscope Records Released on: 2009-01-01 Composer Lyricist: William Adams Composer Lyricist: Allan Pineda Composer Lyricist: Jaime Gomez Composer Lyricist: Stacy Ferguson Composer Lyricist: Bert Berns Auto-generated by YouTube.

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Tonton David · Le blues des racailles · Song · 1991

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National Crime Agency says the ‘threat is getting worse’

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**no copyright infringement intended**